邓婷婷

专职科研人员

教育背景

2009年09月-2013年06月福建师范大学本科

2013年09月-2018年12月中山大学硕博连读

工作经历

2019年04月-2021年06 月深圳市第二人民医院- 博士后

2021年07月-至今深圳市第二人民医院- 专职科研人员

研究方向和兴趣

肿瘤发病机制

顺铂耐药机制

科研项目

1. 2020年国家自然科学基金-青年项目,82002936,30万元,主持。

2. 2020年中国博士后科学基金-面上项目,2020M672833,8万元,主持。

3. 2020年深圳市科技创新基础研究-面上项目,10万元,主持。

4. 2019年中国博士后科学基金-站前特别资助,2019TQ0211,18万元,主持。

5. 2018年国家自然科学基金-面上项目,81871109,54万,参与

代表性成果

(1)Mengfan Tang, Yujing Li, Xiya Zhang, Tingting Deng, Zhifen Zhou, Wenbin Ma and Zhou Songyang. “Structural Maintenance of Chromosomes Joining Flexible Hinge Domain Containing 1(SMCHD1) Promotes Non-homologous End and Inhibits Homologous Recombination Repair upon DNA Damage”, Journal of Biological Chemistry.2014;

(2)Hyeung Kim, Feng Li, Quanyuan He, Tingting Deng, Jun Xu, Feng Jin, Cristian Coarfa, Nagireddy Putluri, Dan Liu, Zhou Songyang. “Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells”, Cell discovery. 2017;

(3)Tingting Deng, Yan Huang, Kai Weng, Song Lin, Yujing Li, Guang Shi, Yali Chen, Junjiu Huang, Dan Liu, Wenbin Ma and Zhou Songyang. “TOE1 acts as a 3’ exonuclease for telomerase RNA and regulates telomere maintenance”, Nucleic Acids Research. 2018;

(4)Xiaoqin Fan, Xina Xie, Ming Yang, Yujie Wang, Hanwei Wu, Tingting Deng, Xin Weng, Weiping Wen and Guohui Nie. “YBX3 Mediates the Metastasis of Nasopharyngeal Carcinoma via PI3K/AKT Signaling”, Frontiers in Oncology”. 2021;

(5)Yingjie Yu, Lidan Li, Guobao Li, Xu Zhou, Tingting Deng, Meng Liang and Guohui Nie.“Intracellular enzyme-powered DNA circuit with a tunable amplifier for miRNA imaging”, Chemical Communications. 2021;

(6)Xiaochan Lu , Tingting Deng, Hongsong Dong, Jinghong Han, Yanping Yu, Deng Xiang, Guohui Nie , and Bing Hu.“Novel Application of Eupatilin for Effectively Attenuating Cisplatin-Induced Auditory Hair Cell Death via Mitochondrial Apoptosis Pathway”, Oxidative Medicine and Cellular Longevity. 2022;

(7)Tingting Deng, Yang Liu , Jialang Zhuang, Yizhe Tang and Qin Huo."ASPM Is a Prognostic Biomarker and Correlates With Immune Infifiltration in Kidney Renal Clear Cell Carcinoma and Liver Hepatocellular Carcinoma”, Frontiers in Oncology. 2022;