Dayong Gu

Director of the Laboratory Department

Clinical Principal Investigator (PI)

Master's Degree Supervisor, Postdoctoral Co-supervisor


PI介绍

MD, Chief Technician. Master's Supervisor in Public Health, Master's Supervisor in Clinical Laboratory Diagnostics, Postdoctoral Co-supervisor at Shenzhen Second People's Hospital Postdoctoral Research Station. Laboratory Assessor for the China National Accreditation Service for Conformity Assessment (CNAS17025), Member of the National Biochemical Testing Standardization Technical Committee (SAC/TC387), Executive Director of the China Society for Inspection and Quarantine, Standing Committee Member of the Nautical Preventive Medicine Special Committee of the Chinese Medical Association's Nautical Medicine Branch, Executive Committee Member of the Basic Laboratory Technology Standardization Branch of the Chinese Medical Promotion Association; Deputy Chairman of the Sensing Technology Subcommittee of the Guangdong Biomedical Engineering Society, Vice Chairman of the Guangdong Society of Tropical Medicine, Member of the Guangdong Medical Association's Laboratory Medicine Branch, Executive Committee Member of the Guangdong Medical Doctor Association's Laboratory Physician Branch; Deputy Chairman of the Laboratory Medicine Branch of the Shenzhen Medical Association, Vice President of the Laboratory Physician Branch of the Shenzhen Medical Doctor Association, Deputy Chairman of the Integrated Medicine Special Committee of the Shenzhen Hospital Managers Association. Primarily engaged in clinical and research work related to molecular diagnostics, having led more than 30 research projects including sub-projects of the National Key R&D Program of the 13th Five-Year Plan, National Natural Science Foundation projects, and provincial and municipal research projects. Holder of more than 30 PCT and invention patents; published over 100 papers (including more than 40 SCI papers); editor and translator of 3 monographs; recipient of 6 provincial and ministerial scientific and technological awards; issued 12 national and industry standards.

工作经历

July 1994 to September 1998: Laboratory Technician at the First Sanatorium of Qingdao, Jinan Military Region

July 2004 to December 2004: Chief Technician at the 401st Hospital of the Jinan Military Region

January 2005 to December 2006: Postdoctoral Researcher at the Department of Life Sciences, Shenzhen Graduate School, Tsinghua University

January 2007 to June 2009: Associate Chief Technician at the 401st Hospital of the Jinan Military Region

July 2009 to March 2019: Chief Physician and Director at the Health Quarantine Center Laboratory of Shenzhen Customs (formerly Shenzhen Entry-Exit Inspection and Quarantine Bureau)

April 2019 to Present: Chief Technician and Director of the Laboratory Department at Shenzhen Second People's Hospital


研究方向和兴趣

Molecular Mechanisms of Immune Response

Molecular Diagnostics and Medical Sensing Technology


科研项目

Guangdong Basic and Applied Basic Research Foundation Enterprise (CapitalBio) Joint Fund (Public Health and Medical Health Field): Development of a Digital PCR System Based on Disc-Type Thermo Oil Circulation Temperature Control Technology. Grant Number: 2021A1515220084. Funding Amount: 200,000 RMB. Principal Investigator.

Shenzhen Science and Technology R&D Fund (International Cooperation Research Project): Construction of a "Insider-Type" Supramolecular Macrophage Delivery Vehicle that Can Penetrate the BBB and Targeted Inhibition of Glioblastoma. Grant Number: GJHZ20200731095604013. Funding Amount: 500,000 RMB. Principal Investigator.

Shenzhen Science and Technology R&D Fund (Shenzhen-Hong Kong Innovation Circle Joint Research Project): Development of a High-Throughput Disc-Type Digital PCR System for On-Site Rapid Detection of Cross-Border Infectious Diseases. Grant Number: SGLH20180625171602058. Funding Amount: 2,000,000 RMB. Principal Investigator.

Shenzhen Science and Technology Plan Project Matching Project: Development of Intelligent Online Detection Technology and Equipment for Multiple Risk Sources in Cross-Border Mail. Grant Number: 201906133000069. Funding Amount: 750,000 RMB. Principal Investigator.


代表性成果

1、Guoliang Xu#, Ruiling Dong#, Dayong Gu#, Huili Tian, Lei Xiong, Zhixun Wang, Wei Wang, Yan Shao, Wenjie Li, Guangyuan Li, Xue Zheng, Yang Yu, Ye Feng, Yuming Dong, Guohua Zhong, Baoping Zhang*, Weimin Li*, Lei Wei*, Chunlei Yang*, Ming Chen*. Selenium Vacancies and Synergistic Effect of Near- and Far-Field-Enabled Ultrasensitive Surface-Enhanced Raman-Scattering-Active Substrates for Malaria Detection. J Phys Chem Lett. 2022 Feb. 10;13(6):1453-1463. Doi:10.1021/acs.jpclett.1c03873. PMID: 35129342.

2、Yanpeng Zhang*, Bing Fan, Yong Luo, Zhiyuan Tao, Yongbo Nie, Yongtao Wang, Fanglin Ding, Yanwu Li*, Dayong Gu*. Comparative analysis of carbapenemases, RND family efflux pumps and biofilm formation potential among Acinetobacter baumannii strains with different carbapenem susceptibility. BMC Infect Dis. 2021 Aug 20;21(1):841. PMID: 34416851. DOI: 10.1186/s12879-021-06529-2.

3、Zhang Y*, Ding F, Luo Y, Fan B, Tao Z, Li Y, Gu D*. Distribution pattern of carbapenemases and solitary contribution to resistance in clinical strains of Acinetobacter baumannii. Ann Palliat Med. 2021 Aug;10(8):9184-9191. doi: 10.21037/apm-21-1805.PMID: 34488404

4、Liang Zhang#, Jian’an He, Tao Li, Xiaocong Wu, Dayong Gu*, Sixiang Zhang*, and Ying Ye. Performance Analysis of a Kretschmann-Based Ag-ITO-Au Surface Plasmon Resonance Sensor through Numerical Simulations. International Journal of Optics. Volume 2021, Article ID 9975877, 10 pages https://doi.org/10.1155/2021/9975877

5、Cheng Gao, Qian Cheng, Junyan Li, Jia Chen, Qingfu Wang, Jianwen Wei, Qiaoxian Huang, Simon M. Y. Lee, Dayong Gu*, Ruibing Wang*. Supramolecular Macrophage-Liposome Marriage for Cell-Hitchhiking Delivery and Immunotherapy of Acute Pneumonia and Melanoma. Adv. Funct. Mater. 26 June 2021. https://doi.org/10.1002/adfm.202102440

6、Ziqing Wang, Weijie Liao, Fuhai Liu, Tingpeng Yang, Weidong Xie, Meijian Liao, Dayong Gu*, Yaou Zhang*. Downregulation of lncRNA EPB41L4A-AS1 Mediates Activation of MYD88-Dependent NF-κB Pathway in Diabetes-Related Inflammation. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2021 Jun.;14:265-277

7、Tao Li#, Jian-an He#, Liang Zhang, Ying Ye, Dayong Gu*, Sixiang Zhang*, Pengjun Zhang, Xuenan Hu, Shuang Wei. Fast Quantitative Analysis of Hidden Dangerous Substances in Mail Based on Specific Interval PLS. Journal of Infrared, Millimeter, and Terahertz Waves.2021May 21; 42:572–587

8、Dayong Gu#, Jianan He#, Jie Sun, Xin Shi, Ying Ye, Zishuai Zhang, Xiangjun Wang, Qun Su, Wenjin Yu, Xiaopeng Yuan*, Ruiling Dong*. The Global Infectious Diseases Epidemic Information Monitoring System: an effective tool for travel health management in China. JMIR Public Health Surveill. 2021 Feb 16;7(2):e24204. DOI: 10.2196/24204. (SCI, IF=3.5)

9、Minghui Ji#, Yun Xia#, Jacky Fong-Chuen Loo*, Lang Li, Ho-Pui Ho, Jianan He* and Dayong Gu*. Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform. RSC Adv. 2020 Sep. 6;10:34088-34098. DOI: 10.1039/D0RA04507A (SCI, IF3.119)

10、Cantong Zhang#, Liancheng Lin#, Donge Tang, Fuju Liu, Meng Li, Qiongying Li, Zhaoxiang Deng, Guohai Chu, Dayong Gu∗, Yong Dai∗. Antibody responses to SARS‐CoV‐2 in healthy individuals returning to Shenzhen. J Med Virol. 2020; 1-4. DOI: 10.1002/ jmv.26355

11、Jianan He#, Lyu Da#, Yining Pan#, Xuanping Tan, Zhitian Li, Feiyue Luo, Weidong Xie∗, Dayong Gu∗. Association between quantitative analyses of periodontal pathogens and the depth of periodontal pockets. Biotechnology & Biotechnological Equipment. 22 Jun 2020; 34:1, 515-521, DOI: 10.1080/13102818.2020.1764387

12、Li Song#, Wei Li#, Jian’an He, Lang Li, Tao Li, Dayong Gu∗ and Huanwen Tang∗. Development of a Pulsed Xenon Ultraviolet Disinfection Device for Real-Time Air Disinfection in Ambulances. Journal of Healthcare Engineering. 2020 Feb 24;2020:6053065.

学术荣誉

Second Prize of the PLA Science and Technology Progress Award

Second Prize of the Guangdong Science and Technology Progress Award

Second Prize of the Guangdong Medical Science and Technology Award

Second Prize of the Shenzhen Science and Technology Progress Award

Shenzhen High-Level Technology Leading Talent