Chief Physician of Neurology, Professor, PhD, Postdoctoral Supervisor, Master's Supervisor. Currently, he is the Vice President of Shenzhen Second People's Hospital (First Affiliated Hospital of Shenzhen University), Head of the Department of Neurology, Deputy Director of the Brain Center, Director of the Stroke Office, and Director of the Shenzhen Stroke Quality Control Center. He serves as the Deputy Director of the Young and Middle-aged Expert Committee of the National Health Commission's Stroke Prevention Project, Head of the Stroke Emergency Group of the Cerebrovascular Disease Branch of the Guangdong Medical Association, Executive Director of the Guangdong Neurological Association, President of the Shenzhen Stroke Association, Deputy Chairman of the Shenzhen Medical Association Neurology Branch, and Director of the Shenzhen Stroke Training Center. He is also an editorial board member of the Chinese Journal of Behavioral Medicine and Brain Science, Chinese Journal of Stroke, International Journal of Cerebrovascular Diseases, and a reviewer for journals such as the International Journal of Hypertension and Stroke and Vascular Neurology.

In recent years, he has made significant contributions to stroke screening, stroke treatment, stroke center construction, clinical stroke research, and medical quality control and improvement in Shenzhen. He has led over 20 projects, published more than 40 professional papers, and holds 2 patents. He has also participated in the compilation of 3 monographs. In 2016, he proposed and created China's first emergency stroke map, the "Shenzhen Thrombolysis Map," which increased the thrombolysis rate for ischemic stroke in Shenzhen from less than 1% to 9.7%. He has received numerous accolades, including the "Top Ten Innovative Youth of Shenzhen" by the Shenzhen Municipal Committee in 2017, the "Outstanding Young and Middle-aged Expert of the Stroke Prevention Project Committee of the National Health and Family Planning Commission" in 2018, the "Top Ten Good Doctors" by the Shenzhen Health Commission, and the Guangdong May Day Labor Medal in 2019. In 2020, as the second principal investigator, he received the "Guangdong Provincial Science and Technology Progress Second Prize" for the project "Key Technologies for Efficient Stroke Prevention and Control and the Construction and Application of a Multidimensional Full-process System."

(1) PhD in Neurology, Southern Medical University, September 2007 - July 2010

(2) Master's in Neurology, Sun Yat-sen University of Medical Sciences, September 1999 - July 2002

(3) Bachelor's in Clinical Medicine, Weifang Medical University, September 1991 - July 1996

Professional Experience:

Resident Physician, Dezhou Second People's Hospital, Shandong
July 1996 - August 1999

Attending Physician, Department of Neurology, Shenzhen Second People's Hospital
July 2002 - November 2007

Associate Chief Physician, Department of Neurology, Shenzhen Second People's Hospital
November 2007 - December 2012

Chief Physician, Department of Neurology, Shenzhen Second People's Hospital
December 2012 - Present

Neurology, with a specific focus on cerebrovascular disease-related epidemiology, chronic diseases, health economics, and health management; clinical research (stroke rehabilitation and care, big data, community studies, wearable devices, virtual reality, artificial intelligence, etc.); basic research (proteomics, molecular biology, nanotechnology).

Shenzhen Key Laboratory of Biomedical Materials Transformation Medicine, Shenzhen Science and Technology Innovation Committee, March 2021 - March 2023, 5 million RMB, ongoing, Principal Investigator

Application Research of VR in Neuroanatomy Teaching, Guangdong Provincial Department of Education Clinical Teaching Base Teaching Reform Research Project, 2021JD102, November 2020 - November 2022, self-funded, ongoing, Principal Investigator

Evaluation Study on the Application of Stroke Emergency Map System in the Treatment of Acute Cerebrovascular Disease Patients, National Brain Protection Committee 2020 China Stroke High-risk Population Intervention Appropriate Technology Research and Promotion Project, GN-2020-R0002, June 2020 - May 2023, 3 million RMB (self-funded), ongoing, Principal Investigator

Research and Application Demonstration of Integrated Stroke Prevention and Treatment Based on Gateway Shift, Shenzhen Science and Technology Innovation Committee Application Demonstration Project, ZXSF201802, June 2018 - June 2021, 5 million RMB, ongoing, Principal Investigator

Research on Precision Imaging Medical Evaluation, Drug Treatment, and Prognosis of Acute Ischemic Cerebrovascular Disease, Shenzhen Science and Technology Innovation Committee, JCYJ20151030151431727, 3 million RMB, January 2016 - December 2018, completed, Principal Investigator

Evaluation and Prognosis Study of Cerebral Blood Flow Autoregulation in Symptomatic Cerebrovascular Narrowing Patients, Shenzhen Health Commission, SZLY2017012, 300,000 RMB, January 2017 - December 2020

Mechanism Exploration of Multimodal Molecular Imaging Technology Monitoring Multifunctional Stem Cell Therapy for Ischemic Stroke, 2013 Guangdong Provincial Science and Technology Plan Project, Principal Investigator

Magnetic Resonance Imaging Thrombolysis Decision-making and Clinical Practice in Hyperacute Phase of Ischemic Stroke, Shenzhen Science and Technology Innovation Committee Basic Research Project, JCYJ20140405201520229, 200,000 RMB, completed, Principal Investigator

Cloud-based Chronic Disease Tracking, Monitoring, and Intervention Management System, Shenzhen Strategic Emerging Industry Development Special Fund Project, JSYY20120831101551583, Principal Investigator

Development of Thrombolysis Intelligent Decision-making System Based on Diffusion-weighted Imaging Analysis, Shenzhen Science and Technology Innovation Committee, CXZZ20140610151856719, Second Principal Investigator

Multi-center Study on Combined Intravenous and Intra-arterial Thrombolysis in Acute Ischemic Stroke, Shenzhen Science and Technology Innovation Committee, Horizontal Cooperation, (Foundation 20150001)

Brain Injury Assessment and Rehabilitation Technology Research Based on Dynamic Cognitive Brain Network Analysis, Shenzhen Science and Technology Innovation Committee, Second Principal Investigator, (Foundation 20170258)

Key Technology of High-resolution MRI for Precision Typing of Ischemic Stroke Causes in Head and Neck, Science and Technology Innovation Committee, Second Principal Investigator, (JCY20180302145700745)

1.Li L, Wang Y, Zeng Y, et al. Multimodal Neuroimaging Predictors of Learning Performance of Sensorimotor Rhythm Up-Regulation Neurofeedback. Front Neurosci. 2021;15:699999. （共同通讯，排名第二，SCI，Q2，IF 4.672）

2.Shiyu Hu, Tao Lan, Yang Wang and Lijie Ren，Individual Insomnia Symptom and Increased Hazard Risk of Cardiocerebral Vascular Diseases: A Meta-Analysis，2021，12: 654719，Front Psychiatry(通讯作者，SCI，Q3，IF 2.85)

3.Zhihao Lei, Shuanglin Li,  Shiyu Hu, and Lijie Ren*，Effects of Baseline Systolic Blood Pressure on Outcome in Ischemic Stroke Patients With Intravenous Thrombolysis Therapy: A Systematic Review and Meta-Analysis.Neurologist 2020,25(3)62-69(通讯作者，SCI，Q4，IF 0.8)

4.Zhihao Lei, Shuanglin Li, Hongye Feng, Yupeng Lai, Yanxia Zhou, Chao Li, Lijie Ren*，Prognostic nomogram for patients with minor stroke and transient ischaemic attack，Postgrad Med J,2020 Sep 11（通讯作者，SCI，Q4，IF 1.9）

5.Shiyu Hu,Tao Lan,Runtao Bai,Shirui Jiang，Jingjing Cai，Lijie Ren*，HSV encephalitis triggered anti-NMDAR encephalitis: a case report，Neurol Sci,2021 Mar;42(3):857-861（通讯作者，SCI，Q4，IF 2.4）

6.Shisheng Ye, Shiyu Hu, Zhihao Lei, Zhichao Li, Weiping Li, Yi Sui, Lijie Ren*, Shenzhen stroke emergency map improves access to rtPA for patients with acute ischaemic stroke. Stroke and Vascular Neurology 2019;0: e000212（通讯作者，SCI, Q1, IF=4.765）.

7.Lijie Ren, Chao Li, Weiping Li, Yixuan Zeng, Shisheng Ye, Zhichao Li, Hongye Feng, Zhihao Lei, Jingjing Cai, Shiyu Hu, Yi Sui,4 Qiang Liu, Bernard M Y Cheung，Fast-tracking acute stroke care in China: Shenzhen Stroke Emergency Map，Postgrad Med J 2019; 95 :46–47. （第一作者，SCI, Q2, IF=1.946）

8.Yang wang ; shiyu hu ; lijie ren* ; zhihao lei; tao lan; jingjing cai , Lp-PLA2 as a risk factor of early neurological deterioration in acute ischemic stroke with TOAST type of large arterial atherosclerosis, Neurological Research, 2018.9.8, 1(8) (通讯作者，SCI, Q3, IF=1.983 )

9.Jingjing Cai,Dan Wu, Yongqian Mo, Anxin Wang,Shiyu Hu,Lijie Ren，Comparison of extracranial artery stenosis and cerebral blood flow assessed by quantitative magnetic resonance, using digital subtraction angiography as reference standard., Medicine. Nov 2016;95(46):e5370. (通讯作者，SCI, Q2, IF=1.87)

10.Hu, Shiyu; Ren Lijie*; Wang, Yilong; Zhang, Runhua; Zhao, Xingquan; Liu, Liping; Li, Weiping; Wang, Yongjun, Homocysteine-lowering therapy and early functional outcomes of ischemic patients with H-type hypertension: a retrospective analysis of CNSR. , Australas Phys Eng Sci Med, 2015.12, 38(4): 785~791 (通讯作者，SCI, Q4, IF=1)

11.Ren, Lijie ; Cai, Jingjing ; Liang, Jie; Li, Weiping ; Sun, Zhonghua , Impact of Cardiovascular Risk Factors on Carotid Intima-Media Thickness and Degree of Severity: A Cross-Sectional Study. , PLoS One, 2015, 10(12) (第一作者，SCI收录)

12.Ren Lijie; Liang Jie; Cai Jingjing; Wu Dan ; Li Weiping , Risk Factors of Stroke in the South of China: A Population-Based Survey of 4563 Residents, Journal of Medical Imaging and Health Informatics, 2017.08, 7(4): 903~908 第一作者，(SCI, Q2, IF=2.776)

13.Zhuoyuan Liang, Lijie Ren*, Ting Wang, Huoyou Hu, Weiping Li, Yaping Wang, Dehong Liu, Yi Lie, Effective management of patients with acute ischemic stroke based on lean production on thrombolytic flow optimization, Australasian Physical & Engineering Sciences in Medicine, 2016 Dec;39(4):987-996. (通讯作者，SCI, Q4, IF=1.171)

14.Shuhua Mua, Lei Hanb,Guangqian Zhou, CuiPing Mo, Junxiu Duan, Zhendan He,Zhiwei Wang, Lijie Ren and Jian Zhang .Protein regulation of induced pluripotent stem cells by transplanting in a Huntington's animal model.Neuropathol Appl Neurobiol. 2016 Feb 9. doi: 10.1111/nan.12315.(共同作者，SCI, Q1, IF=6.878)

15.Li Y, Wang W, Liu T, Ren L, Zhou Y, Yu C, Qu X, and Hu Y, Source analysis of P3a and P3b components to investigate interaction of depression and anxiety in attentional systems. Sci Rep. 2015; 5: 17138. (共同作者，SCI, Q1, IF=4.011)

16.Wang A, Yang Y, Su Z, Yue W, Hao H, Ren L, Wang Y, Cao Y, and Wang Y, Association of Oxidized Low-Density Lipoprotein With Prognosis of Stroke and Stroke Subtypes. Stroke. 2017; 48: 91-97.(共同作者，SCI, Q1, IF=6.046)

17.Liu X, Zhang H, Ren L, et al. Functional assessment of the stenotic carotid artery by CFD-based pressure gradient evaluation. Am J Physiol Heart Circ Physiol. 2016;311(3):H645–H653.  (共同作者，SCI, Q1, IF=4.048)

18.Zhang M, Wu JM, Zhang QS, Yan DW, Ren LJ, Li WP. The association of CYP1A1 genetic polymorphisms and additional gene-gene interaction with ischemic stroke in the eastern Han of China. Neurol Sci. 2016;37(10):1679–1684. (共同作者，SCI, Q3, IF=2.484)

19.Wu D, Xu L, Abbott D, Ren L, et al. Analysis of beat-to-beat blood pressure variability response to the cold pressor test in the offspring of hypertensive and normotensive parents. Hypertens Res. 2017;40(6):581–589. (共同作者，SCI, Q2, IF=3.217)

Current Postdoctoral Fellows: Liu Xia, Zhang Liping, Shan Jingyang, Li Xiuping, Huang Zhengzheng