Researcher, Ph.D. Supervisor. Currently serving as the project leader of the Otolaryngology Research Team at Shenzhen Second People's Hospital, Special-appointed Researcher, and Visiting Professor at Xi'an Jiaotong University. Principal investigator for 4 projects at provincial and ministerial levels. As the first/corresponding author, published over 30 papers in renowned journals such as Nat Catal, Chem Rev, Nat Comm, JACS, Angew Chem, Adv Sci, Nano Today, with a total citation count exceeding 7000, with the H-index reaching 38 (by Nov 2024) and 16 papers enrolled in ESI highly cited papers.

Recipient of the 2018 National Excellent Self-funded Student Scholarship (awarded to 500 students worldwide), selected in 2020 as one of the "Top 2% Scientists Globally," and participated in the National Postdoctoral International Exchange Program in 2019. The work on enhancing tumor immunotherapy through photothermal therapy was recognized as one of the "Top 10 Socially Influential Events in China's Optical Field in 2020."

Education Background:

September 2009 - July 2013:Bachelor's degree in Chemistry from Peking University, supervised by Professor Martin.

August 2013 - April 2018:Ph.D. in Chemistry and Biological Molecular Engineering from the National University of Singapore, supervised by Professor Ning Yan.

The main research focuses on the design and synthesis of single-atom metal enzymes for applications in drug molecule synthesis, catalytic therapy for tumors, and antibacterial and antiviral treatments. The research revolves around loaded single-atom metal catalysts with precise and uniform structures. It includes systematic studies on synthesis strategies, universal rules for stabilizing single atoms, modulation of catalytic performance of single atoms, and their applications. Key achievements include identifying general principles of oxide-supported single-atom metals and applying them in the synthesis of high-value chemicals, atmospheric pollution control, biomass conversion, and biomedical research. Specifically:

Biomedical Field: Nanomedicine, biomaterials, tissue engineering.

Engineering Sciences: Functional polymer materials.

Catalysis: Photocatalysis, enzymatic catalysis, theoretical calculations.

1.2022-2027,National Key Research and Development Program of China, Functional characterization of synthetic microbial systems in the remediation of industrial and medical water pollution, 6,370,000 CNY, person in-charge

2.2023-2025, NSFC Youth Program, Investigation on the application of NIR-responsive titanium-based metal single-atom composite in selective catalysis-promoted synergistic therapy of hypoxic tumor, 300,000 CNY, person in-charge.

3.2019-2022, Department of Science and Technology of Guangdong Province, Investigations on anti-tumor performance of the catalytic platforms of two-dimensional black phosphorus supported metal single-atoms, 100,000 CNY, person in-charge.

4.2019-2024, Guangdong Province Introduction Program for Overseas Young Talents, Investigations on the application of metal single-atom materials supported on phosphorene in cancer phototherapy, 1,000,000 CNY, person in-charge.

5.2019-2021, China Postdoctoral Science Foundation (first class), Investigations on the Application of Metal Single-atom Materials Supported on Phosphorene in Cancer Phototherapy, 120,000 CNY, person in-charge.

6.2019-2021, China Postdoctoral Science Foundation, 2019 International Postdoctoral Exchange Fellowship Program (Talent Introduction Program), 400,000 CNY, person in-charge.

7.2020-2023, Shenzhen Fundamental Research Program-General Project, Application of single metal atom-doped intelligent black phosphorus nanoenzyme in precision cancer therapy, 100,000 CNY, person in-charge.

8.2021-2024, Shenzhen Human Resources and Social Security Bureau of Shenzhen Municipality Fund, 300,000 CNY, person in-charge.

9.2023-2027, Health Commission of Shenzhen Municipality funding, Translational biomedical nanomaterials team led by CAS Academician Xiyun Yan, 15,000,000 CNY, person in- charge.

10.2022-2026, NSFC Major Program, Establishment of novel treatment strategies for sensorineural deafness, 3,000,000 CNY, co-PI.

(1)Bin Zhang; Geng Sun; Shipeng Ding; Hiroyuki Asakura; Jia Zhang; Philippe Sautet^*; Ning Yan^*; “Atomically Dispersed Pt1-Polyoxometalate Catalysts: How Does Metal-Support Interaction Affect Stability and Hydrogenation Activity?”, Journal of the American Chemical Society, 2019, 141(20), 8185-8197.

(2)Bin Zhang; Hiroyuki Asakura, Jia Zhang, Jiaguang Zhang, Sudipta De, and Ning Yan*; “Stabilizing a Platinum1 Single-Atom Catalyst on Supported Phosphomolybdic Acid without Compromising Hydrogenation Activity”, Angewandte Chemie International Edition, 2016, 55, 8319-8323.

(3)Bin Zhang; Taojian Fan; Ni Xie; Guohui Nie; Han Zhang^*;“Versatile Applications of Metal Single-Atom @ 2D Material Nanoplatforms”，Advanced Science, 2019, 6(21): 1901787.

(4)Max J. Hülsey^#; Bin Zhang^#; Zhirui Ma; Hiroyuki Asakura; David A. Do; Wei Chen; Tsunehiro Tanaka; Peng Zhang; Zili Wu; Ning Yan^*;“In situ spectroscopy-guided engineering of rhodium single-atom catalysts for CO oxidation”, Nature Communications, 2019, 10(1330).

(5)Daji Wang^#; Bin Zhang^#; Hui Ding^#; Dan Liu; Jianquan Xiang; Xuejiao J. Gao; Xuehui Chen; Zhongjun Li; Lei Yang; Hongxia Duan; Jiyan Zheng; Zheng Liu; Bing Jiang; Yang Liu; Ni Xie; Han Zhang; Xiyun Yan^*; Kelong Fan^*; Guohui Nie^*;“TiO₂ supported single Ag atoms nanozyme for elimination of SARS-CoV2”，Nano Today, 2021, 40, 101243.

(6) Bin Zhang; Zhenhong Wang; Chunxiang Zhang; Hanwei Wu; Shanshan Dang; Juan Du; Yufeng Song; Han Zhang; Jun Liu*; Guohui Nie*;“Gold Nanocluster-Modified Titanium Nitride for Ultrafast Photonics Applications”，Advanced Electronic Materials, 2021, 7(7), 2000954.

(7)  Max Hülsey^#; Geng Sun^#; Bin Zhang^#; Yao Yu; Shipeng Ding; Sie Shing Wong; Ying Zheng; Shinya Furukawa; Hiroyuki Asakura; Yongqiang Cheng; Zili Wu; Rui Si; Ding Ma; Tsunehiro Tanaka; Philippe Sautet^*; Ning Yan^*;“Low temperature deoxygenation over zero-valent Pd atoms on polyoxometalate”， Nature, 投稿号2021-01-00161, 投稿后审稿意见为大修, Preprint in ChemRxiv, DOI: 10.26434/chemrxiv.13414691.v1)

Postdoctoral researcher: Yang-yang Ju, Xi Wu, Xin Yi

Master's students: Qingdong Zeng, Jingxian Zhao, Yunjiao Jia

Technician: Yanmei Mo, Shanshan Fan

Early Career Editor of Burns & Trauma (IF: 6.3, Q1)

Standing committee member of the Nasopharyngeal Carcinoma Biomarker Committee of the Chinese Anti-Cancer Association

Committee member of the Molecular Diagnostics Branch of the Guangdong Society of Molecular Diagnostics and Translational Medicine

Member of the Youth Hundred Talents Program in the Greater Bay Area of Guangdong Province for Digital Technology Innovation

Reviewer for renowned academic journals in the field of catalysis such as Angewandte Chemie, ACS Nano, Advanced Science, Advanced Functional Materials.